Senior Clinical Research Associate (CRA) Job at Candel Therapeutics, Massachusetts

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  • Candel Therapeutics
  • Massachusetts

Job Description

Why Work With Us?

At Candel, our people drive our success. We value diversity, collaboration, and bold thinking in a supportive, mission-driven environment. We are a high performing team; we show up for each other and stay focused on making a difference for patients and families. Our leadership is transparent and empowering, and our culture is built on trust, flexibility, and accountability, encouraging ownership and innovation every day.

Our Science: Advancing Cancer Immunotherapies

Candel is a clinical-stage biopharma company developing off-the-shelf, multimodal immunotherapies that stimulate personalized, systemic anti-tumor responses. Our platforms use genetically modified adenovirus and HSV constructs. With positive Phase 3 results for our lead candidate, it’s an exciting time to join us and help bring transformative cancer treatments to patients. Learn more:

Position Summary:

If you’re a hands-on, detail-driven clinical research professional who thrives on collaboration and purpose, this
role puts you at the heart of Candel Therapeutics’ mission to advance oncology research. As a Senior Clinical Research Associate (CRA) , you’ll serve as the key link between clinical sites and the Candel team—ensuring that every study runs with precision, integrity, and compassion for the patients at its core.
You’ll play a vital role across multiple oncology programs, overseeing site readiness, patient recruitment, on-site and remote monitoring, and study close-out. Your proactive mindset and ability to think both strategically and tactically will help ensure studies stay compliant, on schedule, and data-driven—while fostering positive, trust-based relationships with investigators and coordinators.

What You’ll Do:

  • Be the bridge between sites and Candel. Act as the primary liaison for all site communications ensuring alignment, transparency, and timely updates between investigators, study staff, and internal teams.
  • Lead site operations end-to-end. Conduct pre-study assessments, initiation visits, on-site and remote monitoring, and study close-outs in full compliance with GCP, SOPs, and FDA regulations.
  • Champion quality and compliance. Verify that data are accurate, complete, and protocol-adherent; ensure all essential documents and training records are current and audit-ready.
  • Drive patient recruitment and retention. Collaborate with sites to develop tailored recruitment strategies and maintain strong participant engagement.
  • Monitor data flow and timelines. Track data entry, query resolution, biospecimen and bioimaging submissions, and safety reporting—proactively resolving issues before they impact deliverables.
  • Partner with CTMs for continuous improvement. Support CAPA implementation for QA findings and contribute insights that strengthen future study execution.
  • Manage site-level operations. Oversee cost tracking, coordinate payments, and maintain accurate documentation throughout the study lifecycle.
  • Collaborate cross-functionally. Work with internal stakeholders to refine study tools, SOPs, and Case Report Forms (CRFs), helping shape best practices that raise the bar for operational excellence.

     

What You Bring

  • Bachelor’s degree required; Master’s preferred in a health-related discipline.
  • 3+ years of experience in oncology clinical trials with strong command of GCP, FDA regulations, and industry best practices. (This is a "must have".)
  • Proven ability to manage multiple studies and databases independently while maintaining high standards of accuracy and efficiency.
  • Excellent communication, organizational, and relationship-building skills—able to influence without authority and navigate complex site dynamics.
  • Strong technical proficiency with Microsoft Office and familiarity with common project management tools.
  • Sound judgment, professionalism, and discretion when handling sensitive or confidential information.

Why You’ll Succeed at Candel:

  • You know how to get things done without needing step-by-step instructions.
  • You value collaboration over ego and strive to lift others as you grow.
  • You’re excited to join a growing company and make a tangible impact.
  • You care about patients, science, and people—in that order .

Work Environment:

This remote role will be based in East coast or mid-west locations preferably for convenience of time zones.

 

Job Tags

Full time, Work at office, Remote work,

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