Job Description

(ID: 2025-1007)

Axle is a bioscience and information technology company that offers advancements in translational research biomedical informatics and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science software engineering and program management we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Benefits We Offer:

• 100% Medical Dental & Vision Coverage for Employees
• Paid Time Off and Paid Holidays
• 401K match up to 5%
• Educational Benefits for Career Growth
• Employee Referral Bonus
• Flexible Spending Accounts:
  • Healthcare (FSA)
  • Parking Reimbursement Account (PRK)
  • Dependent Care Assistant Program (DCAP)
  • Transportation Reimbursement Account (TRN)

Axle is seeking a Senior Data Architect to join our team supporting the National Center for Advancing Translational Sciences (NCATS) located in Rockville MD.

About the Mission

Join the team powering the National COVID Cohort Collaborative (N3C) now expanding into the National Clinical Cohort Collaborative the largest harmonized clinical data resource in the United States. N3C integrates diverse de-identified EHR claims registry and public health data to accelerate discovery and translational research across diseases.

This is not a traditional engineering role. Its a chance to define how clinical data is represented harmonized and made research-ready for thousands of investigators. As a senior architect and informatics leader you will shape national data standards ensure semantic interoperability and help guide the future of data-driven biomedical research.

The Opportunity: Your Impact

As a Senior Data Architect you will lead the design and governance of the data architecture that underpins one of the most ambitious biomedical data resources in existence. Youll ensure that diverse clinical administrative and external datasets are accurately modeled semantically consistent and analytically usable across multiple domains.

You will collaborate closely with informaticians data scientists and data engineers to ensure data are FAIR (Findable Accessible Interoperable and Reusable) and aligned with national data model initiatives.

What Youll Do

Architect and Evolve the National Clinical Data Model

• Lead the design and optimization of scalable data models across diverse healthcare domains.
• Extend and refine OMOP and FHIR vocabularies for evolving data types including genomics imaging and environmental data.
• Define canonical representations of key concepts (diagnoses labs medications encounters outcomes) to ensure semantic integrity across sources.

Advance Data Interoperability and Harmonization

• Oversee cross-model translation between OMOP PCORNet TriNetX ACT and FHIR.
• Govern terminological consistency using SNOMED CT LOINC ICD RxNorm CPT and NDC vocabularies.
• Implement curation pipelines that align heterogeneous data into harmonized analysis-ready structures.

Enable Federated and Privacy-Preserving Research

• Support linkage of de-identified records across clinical systems registries and claims datasets.
• Guide the implementation of privacy-preserving record linkage (PPRL) and federated learning frameworks.
• Collaborate with governance teams to ensure compliance with HIPAA FISMA and NIH data-sharing policies.

Champion Data Quality and Provenance

• Develop frameworks and dashboards for assessing data completeness consistency and validity across contributing sites.
• Define and track metadata standards to ensure reproducibility and transparency.

Provide Strategic Leadership

• Mentor data scientists and engineers in informatics best practices and semantic data design.
• Serve as a liaison to standards development organizations (OHDSI HL7 NCATS CD2H etc.).
  

What Youll Bring (Required Qualifications)

• Masters or Doctoral degree in Biomedical Informatics Health Information Science Computer Science or a related field.
• 6 years of experience in healthcare data architecture data integration or clinical informatics.
• Deep expertise in EHR data clinical terminologies and interoperability standards.
  Demonstrated depth of experience working with OMOP FHIR or other Common Data Models (CDMs) at scale.
• Proficiency in SQL and Python along with collaborative experience with engineers on data transformation workflows.
• Strong understanding of healthcare data sources: EHRs claims registries and observational cohorts.
  Familiarity with data quality frameworks metadata management and data governance principles.
• Proven ability to communicate technical data concepts to scientific and clinical audiences.
  

Preferred Qualifications

• Experience architecting or managing large-scale multi-institutional research data repositories.
• Working knowledge of cloud platforms (AWS GCP or Azure) and modern data architectures (e.g. data lakes knowledge graphs).
• Experience with workflow orchestration tools like Airflow.
• Understanding of federated data systems and distributed query infrastructure.
• Contributions to open-source healthcare informatics projects (e.g. OHDSI HL7).

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills responsibilities duties and/or assignments required. Individuals may be required to perform duties outside of their position job description or responsibilities as needed.

The diversity of Axles employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age race gender religion national origin disability marital status covered veteran status sexual orientation status with respect to public assistance and other characteristics protected under state federal or local law and to deter those who aid abet or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact:

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidates experience qualifications skills and location.

#IND

Salary Range

$125000 - $150000 USD

Required Experience:

Senior IC

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